2019年

嚴慶齡醫學研究論文滙集-2019

1. Yeh, CN; Chen, MH; Chang, YC; Wu, RC; Tsao, LC; Wang, SY; Cheng, CT; Chiang, KC; Chen, TW; Hsiao, M; Weng, WH. Over-expression of TNNI3K is associated with early-stage carcinogenesis of cholangiocarcinoma. Molecular Carcinogenesis 2019;58(2):270-8. 

2. Chen, JL; Chang, CH; Tsai, Jin-Wu. Gli2 Rescues Delays in Brain Development Induced by Kif3a Dysfunction. Cerebral Cortex 2019;29:751-64.

3. Cheng, HW; Hsiao, CT; Chen, YQ; Huang, CM; Chan, SI; Debant, A; Galjart, N; Chiou, A; Kuo, JC. Centrosome guides spatial activation of Rac to control cell polarization and directed cell migration. Life Science Alliance. 2019;2(1):e201800135.

4. Liu, CY; Huang, TT; Chen, YT; Chen, JL; Chu, PY; Huang, CT; Wang, WL; Lau, KY; Dai, MS; Shiau, CW; Tseng, LM. Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progression. EBioMedicine 2019;40:263-75. 

5. Jiang, RS; Lin, WJ. Taste Function in Healthy Taiwanese Adults. Clin Med Insights Ear Nose Throat 2019;12:1179550619845331.

6. Lee, CW; Chen, YJ; Wu, HF; Chung, YJ; Lee, YC; Li, CT; Lin, HC. Ketamine ameliorates severe traumatic event-induced antidepressant-resistant depression in a rat model through ERK activation. Prog Neuropsychopharmacol Biol Psychiatry 2019;93:102-13.

7. Hsieh, YT; Chen, YF; Lin, SC; Chang, KW; Li, WC. Targeting Cellular Metabolism Modulates Head and Neck Oncogenesis. Int J Mol Sci 2019;20:3960.

8. Chen, TY; Hsieh, YT; Huang, JM; Liu, CJ; Chuang, LT; Huang, PC; Kuo, TY; Chia, HY; Chou, CY; Chang, CW; Chen, YF; Chen, HM; Lo, JF; Li, WC. Determination of Pyruvate Metabolic Fates Modulates Head and Neck Tumorigenesis. Neoplasia 2019; 21(7):641-52. 

9. Yang, YP; Nguyen, PNN; Ma, HI; Ho, WJ; Chen, YW; Chien, Y; Yarmishyn, AA; Huang, PI; Lo, WL; Wang, CY; Liu, YY; Lee, YY; Lin, CM; Chen, MT; Wang, ML. Tumor mesenchymal stromal cells regulate cell migration of atypical teratoid rhabdoid tumor through exosome-mediated miR155/SMARCA4 pathway. Cancers 2019;11:720.

10. Lo, CH; Lin, IH; Yang, TT; Huang, YC; Tanos, BE; Chou, PC; Chang, CW; Tsay, YG; Liao, JC; Wang, WJ. Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation. J Cell Biol 2019;218(10):3489-505.

11. Chan, YN; Jheng, YW; Wang, PJ; Chen, CY; Lin, MW; Wang, YJ. Taxane-Induced Peripheral Neuropathy Objective and subjective comparison between paclitaxel and docetaxel in patients with breast cancer. CJON 2019;23(5):494-501. 

12. Yen, CC; Chen, SC; Hung, Y; Wu, PK; Chua, WY; Lin, YC; Yen, CH; Chen, YC; Wang, JRY; Yang, MW; Chao, YE; Chang, MC; Chen, WM. Expression profile-driven discovery of AURKA as a treatment target for liposarcoma. Int J Oncol 2019;55(4):938-48. 

13. Hsu, CC; Chien, KH; Yarmishyn, AA; Buddhakosai, W; Wu, WJ; Lin, TC; Chiou, SH; Chen, JT; Peng, CH; Hwang, DK; Chen, SJ; Chang, YL. Modulation of osmotic stress-induced TRPV1 expression rescues human iPSC-derived retinal ganglion cells through PKA. Stem Cell Research & Therapy 2019;10:284. 

14. Liu, YT; Yen, YJ; Ricardo, F; Chang, Y; Wu, PH; Huang, SJ; Lin, KP; Yu, TY. Biophysical characterization and modulation of Transthyretin Ala97Ser. Annals of Clinical and Translational Neurology 2019;6(10):1961-70.

15. Nian, FS; Li, LL; Cheng, CY; Wu, PC; Lin, YT; Tang, CY; Ren, BS; Tai, CY; Fann, MJ; Kao, LS; Hong, CJ; Tsai, JW. Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B. Molecular Neurobiology 2019;56(9):6095-105.

16. Wang, TT; Beckstead, JW; Yang, CY. Social interaction skills and depressive symptoms in people diagnosed with schizophrenia: The mediating role of auditory hallucinations. Int J Ment Health Nurs 2019; 28(6):1318-27. 

17. Yen, CC; Chen, LT; Li, CF; Chen, SC; Chua, WY; Lin, YC; Yen, CH; Chen, YC; Yang, MH; Chao, Y; Fletcher, JA. Identification of phenothiazine as an ETV1-targeting agent in gastrointestinal stromal tumors using the Connectivity Map. Int J Oncol 2019;55:536-46. 

18. Lin, YM; Chiou, YY; Wu, MH; Huang, SS; Shen, SH. Postablation assessment of hepatocellular carcinoma using dual-energy CT: Comparison of half versus standard iodine contrast medium. PLoS ONE 2019;14(7):e0219577. 

19. Ho, HL; Chou, TY; Yang, SH; Jiang, JK; Chen, WS; Chao, Y; Teng, HW. PD-L1 is a double-edged sword in colorectal cancer: the prognostic value of PD-L1 depends on the cell type expressing PD-L1. J Cancer Res Clin Oncol 2019;145(7):1785-94. 

20. Lin, YC; Huang, C; Huang, HC; Liao, MT; Lai, YH. Metabolomics profiling of haloperidol and validation of thromboxane-related signaling in the early development of zebrafish. Biochem Biophys Res Commun 2019;513(3):608-15. 

21. Wei-Lu; Chen, SJ; Huang, SF; Chan, YJ; Wang, FD; Chen, HP. Clinical significance of human cytomegalovirus viruria and the effect of antiviral therapy in hematopoietic stem cell transplant recipients. J Microbiol Immunol Infect 2019;52(3):402-8.

22. Hung, GY; Horng, JL; Chen, PCH; Lin, LY; Chen, JY; Chuang, PH; Chao, TC; Yen, CC. Incidence of soft tissue sarcoma in Taiwan: A nationwide population-based study (2007-2013). Cancer Epidemiology 2019;60:185-92. 

23. Huang, C; Huang, YL; Wang, CC; Pan, YL; Lai, YH; Huang, HC. Ampelopsins A and C Induce Apoptosis and Metastasis through Downregulating AxL, TYRO3, and FYN Expressions in MDA-MB-231 Breast Cancer Cells. J Agric Food Chem 2019;67:2818-30. 

24. Hsu, PC; Feng, CK; Huang, SH; Chiu, JW; Chou, CL; Yang, TF. Health-related quality of life in children and adolescent with different types of scoliosis: A cross-sectional study. J Chin Med Assoc 2019;82:161-5.

25. Lin, YH; Hung, JJ; Yeh, YC; Hsu, WH. Prognostic significance of basal versus superior segment in patients with completely resected lung adenocarcinoma in the lower lobe. Thoracic Cancer 2019;10:312-20.

26. Hung, KF; Liao, PC; Chen, CK; Chiu, YT; Cheng, DH; Kawasumi, M; Kao, SY; Lo, JF. ASB6 Promotes the Stemness Properties and Sustains Metastatic Potential of Oral Squamous Cell Carcinoma Cells by Attenuating ER Stress. Int J Biol Sci 2019;15(5):1080-90. 

27. Ting, CT; Chen, JW; Chang, MS; Yin, FCP. Arterial Hemodynamics in Prehypertensives. International Journal of Hypertension 2019:3961723. 

28. Liu, CY; Chu, PY; Huang, CT; Chen, JL; Yang, HP; Wang, WL; Lau, KY; Lee, CH; Lan, TY; Huang, TT; Lin, PH; Dai, MS; Tseng, LM. Varlitinib Downregulates HER/ERK Signaling and Induces Apoptosis in Triple Negative Breast Cancer Cells. Cancers 2019;11:105.

29. Lee, YL; Hsu, TF; Jiang, LY; Chao, HT; Wang, PH; Chen, YJ. Transvaginal Natural Orifice Transluminal Endoscopic Surgery for Female-to-Male Transgender Men. J Minim Invasive Gynecol 2019;26(1):135-42.

30. Lin, YT; Chen, LK; Jian, DY; Hsu, TC; Huang, WC; Kuan, TT; Wu, SY; Kwok, CF; Ho, LT; Juan, CC. Visfatin Promotes Monocyte Adhesion by Upregulating ICAM-1 and VCAM-1 Expression in Endothelial Cells via Activation of p38-PI3K-Akt Signaling and Subsequent ROS Production and IKK/NF-κB Activation. Cell Physiol Biochem 2019;52:1398-411. 

31. Hua, MW; Wu, CY; Jiang, RS; Chang, CY; Liang, KL. Validate the classification of fungal rhinosinusitis: A retrospective analysis of 162 patients at a single institution. Clin Otolaryngol 2019;44:1131-7.

32. Chang, WK; Tai, YH; Lin, SP; Wu, HL; Tsou, MY; Chang KY. An investigation of the relationships between postoperative pain trajectories and outcomes after surgery for colorectal cancer. J Chin Med Assoc 2019;82:865-71.

33. Tai, YH; Wu, HL; Lin, SP; Tsou, MY; Chang KY. Influential factors of postoperative pain trajectories in patients receiving intravenous patient-controlled analgesia: a single-centre cohort study in Taiwan. BMJ Open 2019;9:e031936.

34. Chang, WK; Tai, YH; Lin, SP; Wu, HL; Chan, MY; Chang KY. Perioperative blood transfusions are not associated with overall survival in elderly patients receiving surgery for fractured hips. J Chin Med Assoc 2019;82:787-90.

35. Wang, TT; Beckstead, JW; Yang, CY. Social interaction skills and depressive symptoms in people diagnosed with schizophrenia: The mediating role of auditory hallucinations. International Journal of Mental Health Nursing 2019;28:1318-27. 

36. Chiu, YJ; Hsieh, YH; Huang, YH. Improved cell composition deconvolution method of bulk gene expression profiles to quantify subsets of immune cells. BMC Medical Genomics 2019;12(Suppl 8):169.

37. Wu, PC; Fann,MJ; Tran, TT; Chen, S-C; Devina, T; Cheng, IHJ; Lien, CC; Kao, LS; Wang, SJ; Fuh, JL; Tzeng, TT; Huang, CY; Shiao, YJ; Wong, YH. Assessing the therapeutic potential of Graptopetalum paraguayense on Alzheimer’s disease using patient iPSC-derived neurons. Scientific Reports 2019; 9:19301.

38. Kuo, MH; Chang, WW; Yeh, BW; Chu, YS; Lee, YC; Lee, HT. Glucose Transporter 3 Is Essential for the Survival of Breast Cancer Cells in the Brain. Cells 2019;8:1568.

39. Lee, HT; Lee, KI; Chen, CH; Lee, TS. Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer’s disease. Journal of Neuroinflammation 2019;16:267.

40. Kuo, MH; Lee, HF; Tu, YF; Lin, LH; Cheng, YY; Lee, HT. Astaxanthin Ameliorates Ischemic-Hypoxic-Induced Neurotrophin Receptor p75 Upregulation in the Endothelial Cells of Neonatal Mouse Brains. Int. J. Mol. Sci. 2019;20:6168. 

41. Lin, CJ; Saver, JL. Noninferiority Margins in Trials of Thrombectomy Devices for Acute Ischemic Stroke: Is the Bar Being Set Too Low? Stroke 2019;50:3519-26.

42. Hung, JJ; Kao, YS; Huang, CH; Hsu, WH. Overexpression of Aiolos promotes epithelial-mesenchymal transition and cancer stem cell-like properties in lung cancer cells. Sci Rep 2019;9(1):2991.